CLINICAL SIGNS AND SYMPTOMS:
Human toxocariasis has two characteristic
syndromes: visceral larva migrans (VLM) and ocular disease.
VLM can be asymptomatic or can cause a variety of signs and symptoms
including fever, pallor, coughing, wheezing, lassitude, anorexia,
weight loss, hepatomegaly, skin rash, abdominal pain, seizures,
poliomyelitis, and myocarditis. The majority of patients with
the systemic disease do not have ocular involvement (1, 2).
Intraocular infestations with T. canis typically occur
unilaterally in young children. However, it occasionally occurs
bilaterally and/or in adults. Three clinical pictures of ocular
disease are generally described: (1) a raised lesion at or near
the posterior pole; (2) a peripheral granuloma involving retina,
with overlying vitreous opacification and vitreoretinal traction;
(3) diffuse endophthalmitis (2, 3). Other less common presentations
of ocular toxocariasis have been seen in cases of pars planitis,
vitreous abscess, optic neuritis, keratitis, uveities, hypopyon,
or motile larvae in the vitreous cavity (1, 4).
1. Shields JA. Ocular toxocariasis. A review. Surv Ophthalmol
1984; 28:361-81.
2. Dinning WJ, Gillespie SH, Cooling RJ, Maizels RM. Toxocariasis:
a practical approach to management of ocular disease. Eye 1988;
2:580-2.
3. Molk R. Ocular toxocariasis. A review of the literature. Ann
Ophthalmol 1983; 15:216- 31.
4. Gillespie SH, Dinning WJ, Voller A, Crowcroft NS. The spectrum
of ocular toxocariasis. Eye 1993; 7:415-8. |