SELECTED PUBLICATIONS
1. Awasthi N, Wang-Su S, Wagner BJ. Downregulating matrix metalloproteinases 2 and 9 by proteasome inhibition: a possible mechanism for decreasing LEC migration and preventing secondary cataract. Invest Ophthalmol Vis Sci 2008;49:1998-2003.
2. Gupta V, Awasthi N, Wagner BJ. Specific activation of the glucocorticoid receptor and modulation of signal transduction pathways in human lens epithelial cells. Invest Ophthalmol Vis Sci 2007;48:1724-1734.
3. Awasthi N, Wagner BJ. Suppression of human lens epithelial cell proliferation by proteasome inhibition, a potential defense against posterior capsular opacification. Invest Ophthalmol Vis Sci 2006;47:4482-4489.
4. Hosler, Matthew R, Wagner BJ. Role of the proteasome in TGF-beta signaling in lens epithelial cells. Invest Ophthalmol Vis Sci 2006;47:2045-2052.
5. Gupta V, Galante A, Soteropolos P, Guo S, Wagner BJ. Globel profiling reveals novel glucocorticoid induced changes in gene expression of human lens epithelial cells. Mol Vis 2005;11:1018-1040.
6. Awasthi N, Wagner BJ. Upregulation of heat shock protein expression by proteasome inhibition: An antiapoptotic mechanism in the lens. Invest Ophthalmol Vis Sci 2005;46:2082-2091.
7. Rella J, Marcu, S, Wagner BJ. Rapid cyanide detection using the Cyantesmo Kit. J Toxicol 2004:42:897-900.
8. Awasthi N, Wagner BJ. Interferon-gamma induces apoptosis of lens a TN4-1 cells and proteasome inhibition has an antiapoptotic effect. Invest Ophthalmol Vis Sci 2004;45:222-229.
9. Wang-Su ST, McCormack AL, Yang S, Hosler MR, Mixon A, Riviere MA, Wilmarth PA, Andley UP, Garland D, Li H, David L,Wagner BJ. Proteome analysis of lens epithelia, fibers, and the HLE B-3 cell line. Invest Ophthalmol Vis Sci 2003;
44: 4829-4836.
10.
Gupta V, Wagner BJ. Expression of the functional glucocorticoid receptor in mouse and human lens epithelial cells.
Invest Ophthalmol Vis Sci 2003;44:2041-2046.
11. Hosler MR, Wagner BJ. Targeted disruption of specific steps in the ubiquitin-proteasome pathway by oxidation in lens epithelial cells. Intl J Biochem Cell Biol 2003;35:685-697.
12. Singh S, Awasthi N, Egwuagu C, Wagner BJ. Immunoproteasome expression in a non-immune tissue, the ocular lens. Arch Biochem Biophys 2002;405:147-153.
13. Yang S, Wang-Su S-T, Cai H, Wagner BJ. Changes in
three types of ubiquitin mRNA an ubiquitin-protein conjugate
levels during lens development. Exp Eye Res 2002;74:595-604.
14. Su S-T, David LL, Lamp KJ, Yang S, Calvin HI, Garland D,
Andley UP, Wagner BJ. Proteosome comparison of human
lens epithelial cells with cultures HLE B-3 cells. Invest Ophthalmol
Vis Sci 2000;41(4Suppl):S585.
15. Yang SJ, Wang-Su ST, Wagner BJ. Ubiquitin mRNA and
protein levels during lens development. Invest Ophthalmol Vis
Sci 1999;40(4Suppl):S524.
16. Cai H, Howells RD, Wagner
BJ. Identification of a novel gene product specifically
expressed in lens epithelial cells. Mol Vis 1999;5:9999.
17. Cai H, Singh I, Wagner BJ.
Gene expression of the proteasome in lens development. Exp Eye
Res 1998;66: 339-346.
18. Wagner BJ, Wang-Su ST, Sing I and Cai H. Three classes
of ubiquitin mRNA are present in lens cells. Invest Ophthalmol
Vis Sci 1997;38(Suppl):S581.
19. Singh I, Cai H, Wagner BJ.
cDNA cloning of a homologue of human ATPase complex 4, quantitative
tissue distribution and tertiary structure comparison of the
ATPase domain to RecA. Arch Biochem Biophys 1996;333:260.
20. Cai H, Zelenka P, Wagner BJ. Expression of a 20S
proteasome subunit and cyclin B during embryonic
lens development. Invest Ophthalmol Vis Sci 1996;37(Suppl):S981.
21. Cai H, Singh I, Wagner BJ. Evidence of proteasome
involvement in lens development. Invest Ophthalmol Vis Sci 1996;37(Suppl):S981.
22. Wagner BJ, Margolis
JW. Age-dependent association of isolated lens multicatalytic
proteinase complex (proteasome) with heat-shock 90, an endogenous
inhibitor. Arch Biochem Biophys 1995;323:455-462.
23. Wagner BJ, Margolis
JW, Singh I. Lens multicatalytic proteinase complex. Enz Prot 1993;47:202-209.
24. Wagner BJ, Margolis
JW. Thermal stability and activation of lens multicatalytic
proteinase complex (proteasome). Arch Biochem Biophys 1993;307:146-152.
25. Pereira ME, Nguyen T, Wagner
BJ, Margolis JW, Yu B, Wilk S. 3,4-Dichloroisocoumarin-induced
activation of the degradation of beta-casein by the pituitary
multicatalytic proteinase complex. J Biol Chem 1992;267:7949-7955.
26. Wagner BJ, Margolis
JW. Post-translational arginylation in the lens in an experimental
model system. Exp Eye Res 1991;53:609-614.
27. Shivanandappa T, Wagner BJ,
Margolis JW. Conserved N-terminal sequences in homologous subunits
of the multicatalytic proteinase complex (proteasome). Curr
Eye Res 1991;10:871-876.
28. Wagner BJ, Margolis JW, Yin, J. Covalent
labeling of lens multicatalytic proteinase complex with [3H]di-isopropyl
fluorophosphate. Curr Eye Res 1991;10:485-489.
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